Mass spectrometers : puriFlash® MS

AVANT® (U)HPLC

Modular chromatography systems
AIS-MassSpec-Puriflash

Components

  • Gradient Pump
    Autosampler
    UV-Vis detector
    Column oven
    Solvent organizer

Gradient pumps

  • • Quaternary gradient pumps:
    HPLC pumping system maximum 10,000 psi (689 bar)
    UHPLC pumping system maximum 18,850 psi (1,300 bar)
    Flow Rate Range: 1 to 2,000 μL/min
    Flow Accuracy: Better than ± 1% or ± 10 µL whichever is greater
    Flow Precision: 0.075% RSD
    Delay Volume: 691 μL
    Includes vacuum degasser and solvent waste tray.

 

  • • Binary gradient pumps :
    HPLC pumping system maximum 10,000 psi (689 bar)
    UHPLC pumping system maximum 18,850 psi (1,300 bar)
    Flow Rate Range: 1 to 4,000 μL/min
    Flow Accuracy: Better than ± 1% or ± 10 µL whichever is greater
    Flow Precision: 0.075% RSD
    Delay Volume: 50 μL
    Includes automated solvent selection (2 solvents per pump), high pressure mixing, low volume mixer, vacuum degasser and solvent waste tray

Autosamplers

  • • HPLC (10,000 psi)
    • HPLC (10,000 psi) with cooling
    • UHPLC (18,850 psi)
    • UHPLC (18,850 psi) with cooling

 

  • – Capacity:
    2 x 96 or 384 well microtiter plates
    Or 2 x 48 position 2 mL vials
    Optional: 2 x 12 position 10 mL vials

 

  • – Injection modes:
    Full loop
    Partial loop
    µL-pick-up

 

  • – Injection volume:
    Programmable from 0 – 9999 µL in 1 µL increments

 

  • – Injection precision:
    Full loop injection < 0.3% RSD
    Partial loop fill < 0.5% RSD
    µL-pick-up < 0.1% RSD

 

  • – Sample viscosity:
    0.1 to 5 cP

 

  • – Standard syringe volume :
    HPLC 500 µL
    UHPLC 250 µL
    (other options possible)

 

  • – Standard injection loop :
    HPLC 100 µL
    UHPLC 50 µL

 

  • – Injection cycle time:
    Typically <5s

 

  • – Valve switching time :
    60 ms

 

  • – Carry-over :
    <0.05% with standard wash
    <0.01% with additional wash

 

  • – Sample cooling option :
    Minimum: 4 °C ± 2 °C
    Maximum: ambient – 3 °C

UV/Vis Detector

  • UV-DAD diode array detector
    Wavelength range: 190 – 800 nm
    Light source: Deuterium discharge lamp, halogen lamp
    Scanning speed: 20 Hz
    Programmable wavelengths: 8 maximum
    Noise level: 3 x 10-6 AU
    Spectral half-width: 6 nm
    Accuracy adjustment: ± 1 nm
    Reproducibility: ± 0.5 nm

Column Oven

  • • Operating Range 10 °C above ambient to 90 °C – Column Switching Not included
    • Operating Range 10 ºC above ambient to 75 ºC – Column Switching 6-way column selection valve 15,000 psi max
    • Optional diverter valve
    Accuracy ± 1 °C
    Repeatability ± 1 °C
    Stability ± 1 °C
    Column capacity Maximum 6 x 30 cm columns

Software

  • Mass Express
    A user-friendly, intuitive software platform for instrument control and data acquisition
    Data Express
    A full feature data processing package to interpret and present mass spectral and chromatographic information in the clearest form using the fewest possible steps.
    Quant Express (optional)
    Quant Express is an add-on to the Mass Express software suite that provides a complete, detailed quantitation application
    LC express (optional)
    LC Express provides a seamless interface with all Agilent chromatography modules. This, along with Clarity® compatibility, provides integration with nearly all available LC systems.

    Minimum Computer Specifications

    • Operating System: Windows 10 and 11 – 64 bit operating systems.
      Processor:  Intel i3 or greater Intel CPU or AMD equivalent
      Memory: 8 GB
      Hard Disk: >200 GB Hard Drive
      Display: Minimum screen size of 1366 x 768 pixels
      Ports: 4 USB 2.0 (USB Hub is acceptable)
      RJ45 port for Ethernet (or additional USB to RJ45 converter

    Power supply

    • 110 V or 220 V

    Dimensions & weight

    Mass spectrometers puriFlash MS purification
    • Pump: Dimensions: (WxDxH) 330 x 540 x 110 mm
      Weight: 21 kg

      Autosampler: Dimensions (WxDxH) 330 x 510 x 360 mm
      330 x 575 x 360 mm with cooling
      Weight: 19 kg – 21 kg with cooling

      UV-Vis detector: Dimensions (WxDxH) 330 x 510 x 150 mm
      Weight: 9 kg

      Column oven: Dimensions (WxDxH) 170 x 600 x 345 mm
      Weight: 16 kg

      Solvent organizer: Dimensions (WxDxH) 330 x 510 x 80 mm

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