Process Flash purification: puriFlash® 5.015-XL

Process Flash purification: puriFlash® 5.015-XL

5_007-spe-machine-2

puriFlash® 5.015-XL

Optimized for your purifications on a grand scale

Routine Flash purification puriFlash XS 520 Plus interchim
Flow rate
825 ml/min
Routine Flash purification puriFlash XS 520 Plus interchim
Max. pressure
15 bar
  • Small organic molecules 98% 98%
  • Impurity detection 5% 5%
  • Natural products 70% 70%
  • Peptides and oligonucleotides 55% 55%
  • Proteins and biopharmaceuticals 20% 20%
  • Isolation of metabolites 20% 20%
  • Trace enrichment 98% 98%

Components

  • Control unit
  • Pump
  • UV detector
  • Fraction collector
  • Solvent tray with drainage system
  • Integrated column holder (included in the Pack-Process)
  • Integrated Dry-Load holder (included in the Pack-Process)

Pump

  • Flow rate range: 10 ml/min to 825 ml/min
  • Max. operational flow rate: 825 ml/min
  • Optimum flow rate for columns up to F3000 format
  • Flow rate accuracy: +/- 2 % over 100 to 750 mL/min & 5 to 12 bar
  • Flow rate repeatability: < 0.25
  • Flow rate linearity: 0.98 < linearity < 1
  • Pressure range: 0 to 15 bar
  • Max. operational pressure: 15 bar
  • Quaternary gradient valve
  • Gradient tolerance step: < 3.5 %
  • Washing disks

Injection

  • Injection mode: liquid or solid
  • RFID technology: automatic detection of the Dry-Load (included in the Pack-Process)

Detection

  • UV detector 200-400 nm
  • UV detector 200-800 nm (included in the Pack-UVextended)
  • “DAD” technology
  • Multi-wavelength and scan collection over a band of 200 nm (or 600 nm with the Pack-UVextended)
  • Spectral visualization and confirmation of purity
  • Flow cell pathway: 0.3 mm / 80 µl

Column & support compatibility

  • Normal phase(NP)
    Particle sizes: 15 µm, 25 μm, 30 μm, 40 μm , 50 μm
  • Reverse phase (RP)
    Particle sizes: 30 µm, 50 µm
  • .
  • Format: all Flash columns up to F1600 format & Dry-Load up to F0330 format are compatible
  • .
  • Integrated column holder (included in the Pack-Process)
  • Integrated Dry-Load holder (included in the Pack-Process)
  • RFID technology: automatic detection of the columns (included in the Pack-Process)

Fraction collector

  • Capacity:
     3 racks
     42 tubes (29,5 x 200 mm)
  • .
  • Technology:
     Automatic cleaning of the fraction collector needle (to avoid cross-contamination with the previous purification)
     RFID: automatic detection of the racks installed in the fraction collector

Proposed racks

  • Delivery includes a choice of 3 racks from the following list:
  •  Rack for test tubes:
    16 x 150 mm | 18 x 150 mm | 18 x 180 mm |
    21 x 150 mm | 25 x 150 mm | 28 x 150 mm |
    29,5 x 200 mm
  •  Rack for Schott laboratory bottles 250 ml
  • .
  • Position of the numbered tubes (to facilitate identification of tubes)

Software & control unit

  • Control via InterSoft® X software included:
  • Genius, Artificial Intelligence
  • “Flash & Go”™ technology: compatible with our smartphone app “TLC to Flash & Prep”
  • “Boost & Go”™ technology
  • Windows 10
  • Remote control
  • Touchscreen 15″
  • 8 USB ports
  • 2 RJ45 ports
  • Bluetooth/Wi-Fi key

System optimization

  • Tubing after pump: 2.4 mm internal diameter
  • Flow cell pathway: 0.3 mm / 80 µl

Safety

  • System light status
  • Solvent tray with drainage system
  • Level sensor for solvents and waste
  • Retention tray for Dry-Load holder (included in the Pack-Process)
  • Retention tray with leak detectors in the pump, UV detector & fraction collector
  • “Fume Enclosure” technology (allows the use of the purification system without a hood)

Materials in contact with solvents

  • ETFE
  • PTFE
  • 316 L Stainless steel
  • Hastelloy
  • Peek
  • Kalrez
  • Sapphire
  • Ruby
  • Kel-F
  • Zirconium
  • PPS
  • Nitronic 60
  • Borosilicate glass

Accessories box

  • Tubing with fitting & ferrules:
  • Tygon tubing for solvent tray drainage
  • Level sensor tubing (x5)
  • Suction tubes (x4)
  • ETFE tubing 1/8″ mixing chamber to column C1 inlet (not included in the Pack-Process)
  • ETFE tubing 1/8″ mixing chamber outlet to Dry-Load inlet (only in the Pack-Process)
  • ETFE tubing 1/8″ Dry-Load outlet to column inlet (only in the Pack-Process)
  • ETFE tubing 1/8″ fraction collector outlet to waste
  • ETFE tubing 1/8″ draining for fraction collector
  • .
  • Cables:

  • Tygon tubing for solvent tray drainage
  • RFID cable (only in the Pack-Process)
  • USB/USB cable- unit control to fraction collector
  • Power cord – screen to fraction collector
  • HDMI cable – screen to unit control
  • USB/MINI USB cable – screen to unit control
  • LED’S cable – unit control to fraction collector
  • Communication cable Sub-D9 male/female (1 m) – unit control to fraction collecto
  • Communication cable Sub-D9 male/female (0.5 m) – unit control to pump
  • Communication cable Sub-D9 female/female (1 m) – unit control to UV detector
  • Power cord – pump to fraction collector + unit control to fraction collector (x2)
  • General power cable (model according to the country of destination)
  • Support for C1 column base (only in the Pack-Process)

  • Solvent tray
  • Clips P
  • Screw CHC M4x8
  • Grower M4 (x3)
  • Stylus with its clip
  • UV cell test
  • Rear fastening (x2)
  • Screws BHC 4×10 (x2)
  • UV trapdoor
  • ELSD trapdoor
  • Racks (x3)
  • Compliance report

Communication

  • Communication cable Sub-D9 male/female (1 m) – unit control to fraction collector
  • Communication cable Sub-D9 male/female (0.5 m) – unit control to pump
  • Communication cable Sub-D9 female/female (1 m) – unit control to UV detector

Power supply

  • 110 V or 220 V

Dimensions & Weight

  • Weight : 49 kg

Process Flash purification puriFlash 5.007

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